Research Article
Performance of a Novel Blood-Based Early Colorectal Cancer Screening Assay in Remaining Serum after the Blood Biochemical Test
Table 3
Results of ColoDefense in detecting colorectal cancer between different ages, genders, tumor locations, and tumor sizes.
| | SDC2+ (%) | value | SEPT9+ (%) | value | SDC2 or SEPT9+ (%) | value |
| | Age | | | | | | | | <60 () | 86.8 (33/38) | 0.01 | 63.2 (24/38) | 0.09 | 89.5 (34/38) | 0.51 | | ≥60 () | 63.0 (46/73) | 78.1 (57/73) | 84.9 (62/73) | | Gender | | | | | | | | Male () | 73.3 (55/75) | 0.47 | 74.7 (56/75) | 0.56 | 88.0 (66/75) | 0.50 | | Female () | 66.7 (24/36) | 69.4 (25/36) | 83.3 (30/36) | | Location | | | | | | | | Rectum () | 68.3 (41/60) | 0.45 | 66.7 (40/60) | 0.15 | 86.7 (52/60) | 0.85 | | Cecum () | 75.0 (36/48) | 79.2 (38/48) | 85.4 (41/48) | | NA () | 66.7 (2/3) | | 100.0 (3/3) | | 100.0 (3/3) | | | Size | | | | | | | | <3 cm () | 54.6 (6/11) | | 36.4 (4/11) | | 63.6 (7/11) | | | 3-6 cm () | 69.7 (53/76) | | 72.4 (55/76) | | 85.5 (65/76) | | | >6 cm () | 89.5 (17/19) | | 94.7 (18/19) | | 100.0 (19/19) | | | NA () | 100.0 (5/5) | | 80.0 (4/5) | | 100.0 (5/5) | |
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NA: not applicable.
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