The Expression Patterns and Associated Clinical Parameters of Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 and Transmembrane and Immunoglobulin Domain Containing 2 in Oral Squamous Cell Carcinoma

Figure 2

The HHLA2 and TMIGD2 expression levels were independent of OSCC pathology grade, tumor size, and lymph node metastasis. (a) No significant difference in HHLA2 expression was observed among the three pathology grades (I–III: , , and ) of OSCC. (b) No significant difference in TMIGD2 expression was observed among the three pathology grades (I–III: , , and ) of OSCC. (c) The expression levels of HHLA2 in the four stages (T1, T2, T3, and T4: , , , and ) of tumor size showed no significant differences with each other. (d) The expression levels of TMIGD2 in the four stages (T1, T2, T3, and T4: , , , and ) of tumor size showed no significant differences with each other. (e) There was no significant difference between the HHLA2 expression levels in OSCC cases with different lymph node metastasis status (negative: N0, ; positive: N1+N2, ). (f) There was no significant difference between the TMIGD2 expression levels in OSCC cases with different lymph node metastasis status (negative: N0, ; positive: N1+N2, ).

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