Urine 5MedC, a Marker of DNA Methylation, in the Progression of Chronic Kidney Disease

Figure 1

Urine 5MedC and CKD stages. Box and line plots showing the levels of urine 5MedC (μmol/gCr) according to the CKD stages (early to middle stages 1 to 3 or later stages 4 and 5) based on the estimated glomerular filtration rate. The boxes denote the medians and 25th and 75th percentiles. The lines mark the 5th and 95th percentiles. Wilcoxon’s test. CKD: chronic kidney disease; 5MedC: 5-methyl-2-deoxycytidine.