Prognostic Value of BIRC5 in Lung Adenocarcinoma Lacking EGFR, KRAS, and ALK Mutations by Integrated Bioinformatics Analysis

Figure 4

mRNA expression of hub genes. (a) The mRNA expression of 9 hub genes (TOP2A, BIRC5, KIAA0101, CDC20, UBE2C, AURKA, TRIP13, MCM4, and KIF20) between LAD and normal tissues based on the UCSC Xena database. 5 hub genes, namely, BIRC5 (b), MCM4 (c), CDC20 (d), KIAA0101 (e), and TIRP13 (f), were more significantly upregulated in triple-negative (TN) lung adenocarcinomas based on TCGA database than in non-triple-negative (non-TN) lung adenocarcinomas.

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