Research Article
High Membranous Expression of Fatty Acid Transport Protein 4 Is Associated with Tumorigenesis and Tumor Progression in Clear Cell Renal Cell Carcinoma
Table 2
CD36, FATP4, and ACSL1 expressions in RCC cases.
| | Characteristics | CD36 (%) | FATP4 (%) | ACSL1 (%) | | High () | Low () | value | High () | Low () | value | High () | Low () | value |
| | Age | | | | | | | | | | | Low (<60 yr) | 42 (56.8) | 60 (56.6) | 0.984 | 43 (50.6) | 59 (62.1) | 0.120 | 40 (55.6) | 62 (57.4) | 0.806 | | High (≥60 yr) | 32 (43.2) | 46 (43.4) | | 42 (49.4) | 36 (37.9) | | 32 (44.4) | 46 (42.6) | | | Gender | | | | | | | | | | | Male | 52 (70.3) | 75 (70.8) | 0.944 | 54 (63.5) | 73 (76.8) | 0.05 | 44 (61.1) | 83 (76.9) | 0.023 | | Female | 22 (29.7) | 31 (29.2) | | 31 (36.5) | 22 (23.2) | | 28 (38.9) | 25 (23.1) | | | Grade | | | | | | | | | | | Low | 12 (16.2) | 22 (20.8) | 0.444 | 13 (15.3) | 21 (22.1) | 0.244 | 12 (16.7) | 22 (20.4) | 0.534 | | High | 62 (83.8) | 84 (79.2) | | 72 (84.7) | 74 (77.9) | | 60 (83.3) | 86 (79.6) | | | TNM stage | | | | | | | | | | | Low (I, II) | 58 (78.4) | 87 (82.1) | 0.537 | 63 (74.1) | 82 (86.3) | 0.039 | 55 (76.4) | 90 (83.3) | 0.249 | | High (III, IV) | 16 (21.6) | 19 (17.9) | | 22 (25.9) | 13 (13.7) | | 17 (23.6) | 18 (16.7) | | | Metastasis | | | | | | | | | | | Absent | 71 (95.9) | 99 (93.4) | 0.529 | 80 (94.1) | 90 (94.7) | 1.000 | 67 (93.1) | 103 (95.4) | 0.524 | | Present | 3 (4.1) | 7 (6.6) | | 5 (5.9) | 5 (5.3) | | 5 (6.9) | 5 (4.6) | | | Tumor necrosis | | | | | | | | | | | Absent | 65 (87.8) | 95 (89.6) | 0.708 | 70 (82.4) | 90 (94.7) | 0.009 | 64 (88.9) | 96 (88.9) | 1.000 | | Present | 9 (12.2) | 11 (10.4) | | 15 (17.6) | 5 (5.3) | | 8 (11.1) | 12 (11.1) | | | Sarcomatoid feature | | | | | | | | | | | Absent | 70 (94.6) | 101 (95.3) | 1.000 | 81 (95.3) | 90 (94.7) | 1.000 | 70 (97.2) | 101 (93.5) | 0.319 | | Present | 4 (5.4) | 5 (4.7) | | 4 (4.7) | 5 (5.3) | | 2 (2.8) | 7 (6.5) | | | Recurrence | | | | | | | | | | | Absent | 61 (82.4) | 86 (81.1) | 0.824 | 64 (75.3) | 83 (87.4) | 0.037 | 61 (84.7) | 86 (79.6) | 0.387 | | Present | 13 (17.6) | 20 (18.9) | | 21 (24.7) | 12 (12.6) | | 11 (15.3) | 22 (20.4) | |
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RCC: clear cell renal cell carcinoma; TNM: tumor-node-metastasis.
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