Polymorphisms -455G/A and -148C/T and Fibrinogen Plasmatic Level as Risk Markers of Coronary Disease and Major Adverse Cardiovascular Events

Table 1

Basal characteristics of the study population.

Characteristic	Controls^a; (%)	SCD^b; (%)	UCD^c; (%)	value
Age (yr, ±SD)				NS
Female	29 (35.8)	23 (33.8)	17 (34)	NS
Male	52 (64.2)	45 (66.2)	33 (66)
Familiar antecedents
Diabetes	26 (32.1)	26 (38.2)	27 (50)	0.043
CD	13 (16.0)	35 (51.5)	15 (30)	<0.00001
Hypertension	23 (28.4)	30 (44.1)	23 (46)	NS
Risk factors
Diabetes	16 (19.8)	38 (55.9)	27 (54)	<0.00001
Hypertension	27 (33.3)	42 (61.8)	30 (60)	0.00062
Smoking	23 (28.4)	31 (45.6)	27 (54)	0.00901
Dyslipidemia	3 (3.7)	14 (20.6)	13 (26)	<0.00010
Sedentary life	44 (54.3)	37 (54.4)	29 (58)	NS
BMI				NS
Index event
ST elevation	—	—	29 (58)
Non-ST elevation	—	—	21 (42)
Biochemical variable
Fibrinogen (mg/dl)				0.001

NS = not significant ().