Comparing MicroRNA Profilings of Purified HER-2-Negative and HER-2-Positive Cells Validates miR-362-5p/Sema3A as Characteristic Molecular Change in Triple-Negative Breast Cancers

<div>Representative images from in situ hybridization and immunohistochemistry both in the same location of tissue microarray (a). miR-362-5p expression was significantly negatively correlated with the Sema3A expression (b). Relative miR-362-5p expression in the MDA-MB-468 cell line (triple-negative) and SK-BR-3 cell line (HER-2<sup>+</sup>) assessed by quantitative real-time PCR analysis; experiments were repeated three times (C1); Sema3A protein expression in the MDA-MB-468 cell line and SK-BR-3 cell line was assessed by detection by Western blot (C2).</div>

Disease Markers

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Figure 5

Figure 5: Comparing MicroRNA Profilings of Purified HER-2-Negative and HER-2-Positive Cells Validates miR-362-5p/Sema3A as Characteristic Molecular Change in Triple-Negative Breast Cancers 

Figure 5 | Comparing MicroRNA Profilings of Purified HER-2-Negative and HER-2-Positive Cells Validates miR-362-5p/Sema3A as Characteristic Molecular Change in Triple-Negative Breast Cancers 