Circulating MicroRNA-499 as a Diagnostic Biomarker for Acute Myocardial Infarction: A Meta-analysis

Table 1

Information of the included studies.

Author	Year	Country	Specimen	Case/control	Biomarkers	Sensitivity	Specificity
Corsten et al. [15]	2010	Luxembourg	Plasma	32/36	miR-499	84	95
Wang et al. [16]	2010	China	Plasma	33/33	miR-499	36.4	100
Devaux et al. [17]	2012	Luxembourg	Plasma	510/87	miR-499	100	100
Gidlöf et al. [18]	2013	Sweden	Plasma	319/88	miR-499	64	90
					cTnT	95	85
Li et al. [19]	2013	China	Plasma	67/32	miR-499	80	94
					cTnT	96	100
Devaux et al. [20]	2015	Luxembourg	Plasma	224/931	miR-499	35.7	90.3
					cTnT	70	96
Ji et al. [21]	2015	China	Serum	98/23	miR-499	53	100
					cTnT	94	82
Liu et al. [22]	2015	China	Plasma	70/72	miR-499	82.1	94
Zhao et al. [23]	2015	China	Plasma	59/60	miR-499	86.37	93.47
					cTnT	93.12	100
Zhang et al. [24]	2015	China	Plasma	142/85	miR-499	80	80.28
					cTnT	100	82
Shalaby et al. [25]	2016	Egypt	Serum	48/25	miR-499	93.4	100
Agiannitopoulos et al. [26]	2017	Egypt	Serum	110/121	miR-499	75	97.2
Fawzy et al. [27]	2018	Greece	Plasma	80/50	miR-499	98	100
					cTnT	94	100
Liu et al. [28]	2018	China	Plasma	145/30	miR-499	98	100