ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease

Table 3

Association between cytokines, clinical characteristics, and the presence of acute CAD was assessed by simple linear regression analysis and subsequent binary linear regression analysis.

Variables	Simple linear			Binary linear
		95% CI	value		95% CI	value
ADAMTS-5	-0.518	-0.653 to -0.383	<0.001	-0.352	-0.081 to -0.032	<0.001
MMP-2	0.361	0.214 to 0.508	<0.001	0.147	0.000 to 0.024	0.045
MMP-9	0.365	0.219 to 0.512	<0.001	0.163	0.000 to 0.004	0.028
CRP	0.303	0.153 to 0.454	<0.001	0.144	0.000 to 0.014	0.041
Gender	-0.068	-0.225 to 0.090	0.397
Age	0.123	-0.034 to 0.279	0.124
Smoking	-0.133	-0.289 to 0.023	0.094
SBP	-0.030	-0.187 to 0.128	0.712
DBP	0.013	-0.145 to 0.171	0.871
Glu	0.010	-0.100 to 0.121	0.855
TC	-0.071	-0.228 to 0.086	0.375
TG	0.024	-0.134 to 0.181	0.766
HDL-C	-0.095	-0.252 to 0.061	0.231
LDL-C	-0.082	-0.239 to 0.075	0.304

ADAMTS-5: a disintegrin and metalloproteinase with thrombospondin type 1 motif-5; MMP-2: matrix metalloproteinase-2; MMP-9: matrix metalloproteinase-9; CRP: C-reactive protein; SBP: systolic blood pressure; DBP: diastolic blood pressure; Glu: fasting glucose; TC: total cholesterol; TG: total triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.