Research Article

PCDHGB7 Increases Chemosensitivity to Carboplatin by Inhibiting HSPA9 via Inducing Apoptosis in Breast Cancer

Figure 3

HSPA9 levels in Hs578T and BT549 cells with PCDHGB7 overexpression and PCDHGB7 knockdown. (a) HSPA9 mRNA levels are elevated in Hs578T cells with PCDHGB7 knockdown and reduced when PCDHGB7 is overexpressed. (b) The mRNA level of HSPA9 increased in PCDHGB7 knockdown BT549 cells and decreased in Hs578T cells with PCDHGB7 overexpression. (c) HSPA9 protein levels are elevated in Hs578T cells with PCDHGB7 knockdown and reduced in Hs578T cells with PCDHGB7 overexpression. (d). HSPA9 protein levels are increased in BT549 cells with PCDHGB7 knockdown and decreased in BT549 cells with PCDHGB7 overexpression. Data are presented as the from three independent experiments. The representative WB images are presented at the top panel (, , and ).
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