PCDHGB7 Increases Chemosensitivity to Carboplatin by Inhibiting HSPA9 via Inducing Apoptosis in Breast Cancer

<div>Construction of HSPA9 knockdown cell models in two BC cell lines, Hs578T and BT549, and the chemosensitivity assay in breast cells after exposure to different concentrations of carboplatin. The effects of HSPA9 knockdown were verified by real-time PCR and WB in Hs578T (a, c) and BT549 cells (b, d). (e, f) Carboplatin sensitivity in BC and HSPA9 knockdown breast cancer cells is assessed by CCK-8 assay. Chemosensitivity is significantly increased in Hs578T (e) and BT549 (f) breast cancer cells with abrogated HSPA9 expression. 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Disease Markers

fig6

Figure 6

Figure 6: PCDHGB7 Increases Chemosensitivity to Carboplatin by Inhibiting HSPA9 via Inducing Apoptosis in Breast Cancer 