Secreted Frizzled-Related Protein 2 Is Associated with Disease Progression and Poor Prognosis in Breast Cancer

Table 1

Clinicopathological characteristics of the study cohort.

Characteristics	No. of patients	(%)	No. of controls	(%)
Age (years)
≤45	131	47.8	80	54.4
>45	143	52.2	67	45.6
Menopausal status
Premenopausal	166	60.6	96	65.3
Postmenopausal	108	39.4	51	34.7
Tumor size (cm)
≤2	79	28.8
>2	173	63.2
Undetermined	22	8.0
Histology
IDC	213	77.8
DCIS	59	21.5
Other	2	0.7
TNM stage
I+II	97	35.4
III	155	56.6
Undetermined	22	8.0
Lymph node metastases
Negative	133	48.6
Positive	136	49.6
Unknown	5	1.8
ER
Negative	97	35.4
Positive	172	62.8
Unknown	5	1.8
PR
Negative	120	43.8
Positive	149	54.4
Unknown	5	1.8
HER2
Negative	198	72.3
Positive	71	25.8
Unknown	5	1.9
Ki67
≤14%	105	38.3
>14%	164	59.8
Unknown	5	1.9

Abbreviations: IDC: invasive ductal carcinoma; DCIS: ductal carcinoma in situ; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2.