Secreted Frizzled-Related Protein 2 Is Associated with Disease Progression and Poor Prognosis in Breast Cancer

Table 2

The association of serum sFRP2 levels with clinicopathological characteristics in breast cancer patients.

Characteristics	Number	sFRP2 (, ng/mL)
Patient group	274		<0.0001
Control group	147
Age (years)
≤45	131		0.2415
>45	143
Menopausal status
Premenopausal	166		0.1815
Postmenopausal	108
Tumor size (cm)
≤2	79		0.0118
>2	173
Histology
IDC	213		0.8597
DCIS	59
TNM stage
I+II	97		0.0023
III	155
Lymph node metastases
Negative	133		<0.0001
Positive	136
ER
Negative	97		0.1572
Positive	172
PR
Negative	120		0.5532
Positive	149
HER2
Negative	198		0.3460
Positive	71
Ki67
≤14%	105		0.0253
>14%	164