CDK5RAP3 Participates in Autophagy Regulation and Is Downregulated in Renal Cancer

Figure 3

CDK5RAP3 regulates autophagy in renal cancer cells. (a, b) Endogenous CDK5RAP3 in Caki-1 and 769-P cells was infected with adenoviral vectors carrying CDK5RAP3 for overexpression (a) or knocked down (b) with two specific siRNAs (seq1 and seq2). The conversion of LC3 was detected using western blotting.

(a)

(b)