Association of Common Variants in HNF1A Gene with Serum AFP Level in Healthy Chinese Individuals and HCC Patients

Table 5

Comparison of genotype frequencies among Chinese HCC patients according to AFP concentrations with the .

Genotype	(); (%)	(); (%)	^1	^2
rs2464196
GG	8 (11.8)	34 (29.1)	0.007	0.024
GA	42 (61.7)	56 (47.8)	0.068
AA	18 (26.5)	27 (23.1)	0.604
GA+AA	60 (88.2)	83 (70.9)	0.007
rs1169310
CC	7 (10.3)	33 (28.2)	0.004	0.017
CT	43 (63.2)	58 (49.6)	0.072
TT	18 (26.5)	26 (22.2)	0.513
CT+TT	61 (89.7)	84 (71.8)	0.004

¹ represents the difference in genotype frequencies of rs2464196 and rs1169310 between the groups with and without ; Chi-squared tests were adopted. ² represents the difference in the distribution of rs2464196 and rs1169310 between the two groups; Chi-squared tests were used.