miR-34b/c rs4938723 T>C Decreases Neuroblastoma Risk: A Replication Study in the Hunan Children

Table 1

miR34b/c rs4938723 T>C polymorphism and neuroblastoma susceptibility.

Genotype	Cases ()	Controls ()	^a	Crude OR (95% CI)		Adjusted OR (95% CI)^b	^b
rs4938723 T>C ()
TT	100 (61.73)	117 (43.33)		1.00		1.00
TC	47 (29.01)	123 (45.56)		0.45 (0.29-0.69)	0.0002	0.46 (0.30-0.71)	0.0004
CC	15 (9.26)	30 (11.11)		0.59 (0.30-1.15)	0.119	0.62 (0.32-1.23)	0.175
Additive			0.0008	0.62 (0.46-0.85)	0.0026	0.64 (0.47-0.88)	0.005
Dominant	62 (38.27)	153 (56.67)	0.0002	0.47 (0.32-0.71)	0.0002	0.49 (0.33-0.73)	0.0005
Recessive	147 (90.74)	240 (88.89)	0.542	0.82 (0.43-1.57)	0.542	0.86 (0.45-1.67)	0.665

OR: odds ratio; CI: confidence interval.^a test for genotype distributions between neuroblastoma cases and cancer-free controls.^bAdjusted for age and gender.