DIAPH1 Is Upregulated and Inhibits Cell Apoptosis through ATR/p53/Caspase-3 Signaling Pathway in Laryngeal Squamous Cell Carcinoma

Figure 4

DIAPH1 knockdown promoted apoptosis via ATR/p53/caspase-3 signaling pathway. (a) Western blot analysis of ATR, p-p53, Bax, and cleaved caspase-3, -8, and -9 in DIAPH1 knockdown (SH1) and control (NC) of AMC-HN-8 and FD-LSC-1 cells. Numbers labelled under the bands were the relative expression and the relative expression of NC cells was set as 1. (b) The schematic graph of apoptotic signaling pathway mediated by DIAPH1.

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