The Triglyceride-Glucose Index Predicts Coronary Artery Disease Severity and Cardiovascular Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome

Table 7

Association between the TyG index and outcomes.

Outcome variables	Unadjusted		Adjusted model 1		Adjusted model 2
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
MACEs	1.951 (1.416–2.688)	<0.001	1.970 (1.431–2.712)	<0.001	1.878 (1.130–3.121)	0.015
Cardiac death	2.285 (1.195–4.371)	0.012	2.304 (1.217–4.362)	0.010	2.461 (0.852–7.110)	0.096
Nonfatal MI	1.399 (0.717–2.731)	0.325	1.409 (0.715–2.777)	0.322	2.557 (0.790–8.280)	0.117
TVR	2.258 (1.285–3.968)	0.005	2.204 (1.267–3.835)	0.005	1.904 (0.760–4.771)	0.169
Congestive heart failure	1.015 (0.374–2.753)	0.977	0.989 (0.351–2.790)	0.984	0.413 (0.083–2.056)	0.280
Nonfatal stroke	4.421 (1.559–12.536)	0.005	4.803 (1.631–14.145)	0.004	3.082 (0.714–13.309)	0.132

Univariate and multivariate Cox proportional hazards regression analyses are applied. Model 1 is adjusted for age and gender. Model 2 is adjusted for model 1, metabolic syndrome, LDL-C, HDL-C, SYNTAX score, CRP, basal insulin, sulfonylurea, metformin, α-glucosidase inhibitor, ACEI/ARB, beta-blocker, and PCI/CABG. Abbreviations: MACEs: major adverse cardiovascular events; MI: myocardial infarction; TVR: target vessel revascularization.