Prostatic Acid Phosphatase (PAP) Predicts Prostate Cancer Progress in a Population-Based Study: The Renewal of PAP?
Table 1
Incidence proportion and median of patients with PAP-positive (PAP+) and PAP-negative (PAP-).
PAP+ median (IQR)
No. (%) 5184, 100
PAP- median (IQR)
No. (%) 3161, 100
Total
value
Age at diagnosis (y)
30-50
48 (45-50)
161, 3.11
48 (46-50)
131, 4.14
292
0.365
51-70
63 (58-67)
2857, 55.11
63 (58-67)
1927, 60.96
4784
0.968
71-85
76 (73-79)
1972, 38.04
76 (73-78)
1037, 32.81
3009
0.025
≥86
88.5 (87-91)
194, 3.74
88 (87-90)
66, 2.09
260
0.071
Total
5184, 100
3161, 100
Race
White
NA
3838, 74.73
NA
2371, 75.41
6209
NA
Black
NA
1021, 19.88
NA
452, 14.38
1473
Asian
NA
259,5.04
NA
304,9.67
563
American Indian
NA
18, 0.35
NA
17, 0.54
35
Total
NA
5136, 100
NA
3144, 100
8280
NA
1362, 42.30
NA
791, 38.44
2153
0.03
NA
1229, 38.17
NA
855,41.55
2084
NA
440,13.66
NA
297,14.43
737
NA
189, 5.87
NA
115,5.9
304
Total
NA
3220, 100
NA
2058, 100
5278
NA
3804, 98.81
NA
2605, 99.09
6409
0.005
NA
46, 1.19
NA
24, 0.91
38
Total
NA
3850, 100
NA
2629, 100
6479
NA
4450, 89.07
NA
2974, 95.94
7424
<0.001
NA
546, 10.93
NA
126,4.6
672
Total
NA
4996, 100
NA
3100, 100
8096
Invasion
No invasion
NA
4185, 3.92
NA
2878, 92.87
7063
<0.001
Invasion beyond capsule
NA
242,4.85
NA
94, 3.03
336
Distant metastasis
NA
560, 11.23
NA
127, 4.10
687
Total
NA
4987,100
NA
3099, 100
8086
Grade
1
NA
174,3.66
NA
143,4.66
317
2
NA
3052, 64.23
NA
2197, 71.56
5249
<0.001
3
NA
1498, 31.52
NA
711,23.16
2209
4
NA
28, 0.59
NA
19, 0.62
47
Total
NA
4752, 100
NA
3070, 100
7822
Number of localized tumors
1.0 (1.0-1.0)
5184,100
1.0 (1.0-2.0)
3161, 100
8345
<0.001
Survival months (all-cause)
134.0 (63.0-161.0)
4761, 100
143.0 (88.0-166.0)
2821, 100
7582
<0.001
Survival months (prostate cancer-specific)
47.00 (16.00-90.00)
963, 100
93.00 (52.75-132.00)
962, 100
1925
<0.001
Survival months (postsurgical)
144.0 (95.0-168.0)
1642, 100
152.0 (125.8-172.0)
1118, 100
2760
<0.001
To value the PAP+/- ratio of each subgroups, the total effective patient number of each group is calculated. As the data were measurement data and ranked data, the Mann-Whitney Sum test was utilized. Abbreviations: + denotes positive; − denotes negative; PAP: prostatic acid phosphatase; TNM: tumor-node-metastasis; No.: number; %: percent; ;.
