High Expression of RARβ Is a Favorable Factor in Colorectal Cancer

Table 2

Univariate and multivariate analysis of prognostic factors for overall survival in CRC patients.

Characteristic	Univariate analysis			Multivariate analysis
	HR		95% CI	HR		95% CI
RARβ expression	0.032	0.001	0.004 0.232	0.038	0.001	0.005 0.278
Tumor diameter (cm); ≤2 vs >2	4.596	0.132
Lymph node metastasis; No metastasis vs metastasis	1.379	0.268	0.781 2.434
Distant metastasis (M); No metastasis vs metastasis	5.189	0.001	2.028 13.272
Stage grouping with TNM; Stage I vs II vs III-IV	1.758	0.002	1.235 2.503	1.523	0.030	1.043 2.225
Gender; Male vs female	1.584	0.148	0.849 2.953
Age at diagnosis (years); ≤60 vs >60	1.121	0.708	0.615 2.044
Differentiation; Well vs moderate vs poorly	0.418	0.006	0.224 0.780	0.687	0.243	0.366 1.289

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