Role of Circular RNAs in Preeclampsia

Figure 1

circRNAs are generated from back-splicing of exons, introns, or both, to form circular exonic circRNAs (EcircRNAs), circular intronic RNAs (ciRNAs), and exon-intron circRNAs (EIciRNAs). The functions of circRNAs include acting as microRNA (miRNA) sponges or competing endogenous RNA, interacting with RNA-binding proteins (RBPs), and regulating gene transcription and mRNA translation.