PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement

Figure 6

Age-adjusted Kaplan-Meyer cancer-specific survival curves for RB1 expression in LN- patients (a), AKT3 expression in LN- patients (b), AKT3 expression in luminal A patients (c), and AKT2 expression in luminal B patients (d). Graphs in (c) and (d) are irrespective of the LN+ and/or LN- group. The gene expression was dichotomized in low expression and high expression for the median value of each transcript. The graphs of the survivor function were adjusted to the mean age of patients (46.9 years). CSS: cancer-specific survival ( values on the graph refer to the log-rank test).

(a)

(b)

(c)

(d)