Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

Figure 6

Association between adipose tissue IL-33 and CCL7 and CCL8 in individuals with varying degrees of glycemia. (a) IL-33 was inversely correlated with CCL7 in individuals with normoglycemia () but not in those with prediabetes () or T2D (). (b) Higher levels of IL-33 were associated with significantly lower CCL7 in individuals with normoglycemia but not in those with prediabetes or T2D. (c) IL-33 was inversely correlated with CCL8 in individuals with normoglycemia () but not in those with prediabetes () or T2D (). (d) Higher levels of IL-33 were associated with lower CCL8 in individuals with normoglycemia (although statistically nonsignificant) but not in those with prediabetes or T2D. IL-33: interleukin-33; CCL7: chemokine (C-C motif) ligand 7; CCL8: chemokine (C-C motif) ligand 8; NL: normoglycemia; T2D: type 2 diabetes; Meds: glucose-lowering medications.

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