Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia

Figure 7

Association between adipose tissue IL-33 and IL-6 and IL-12A in individuals with varying degrees of glycemia. (a) IL-33 was directly correlated with IL-6 (although statistically nonsignificant) in individuals with normoglycemia (), prediabetes (), and T2D (). (b) Higher levels of IL-33 were associated with significantly higher IL-6 in individuals with normoglycemia but not in those with prediabetes or T2D. (c) IL-33 was directly correlated with IL-12A in individuals with T2D () but not in those with normoglycemia () or prediabetes (). (d) Higher levels of IL-33 were associated with significantly higher IL-12A in individuals with T2D (although statistically nonsignificant) but not in those with normoglycemia or prediabetes. IL-33: interleukin-33; IL-6: interleukin-6; IL-12A: interleukin-12A; T2D: type 2 diabetes; Meds: glucose-lowering medications.

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