Research Article
CACNA1C Polymorphism (rs2283291) Is Associated with Schizophrenia in Chinese Males: A Case-Control Study
Table 2
Association analysis of SNPs (rs2283291 and rs4648635) with SCZ as stratified by the famine exposure (n (%)).
| | Genotype/allele | Famine | Nonfamine | | SCZ () | HC () | | | SCZ () | HC () | | |
| | rs2283291 | | | | | | | | | | GG | 106 (47.1) | 117 (47.2) | 2.386 | 0.303 | 94 (42.7) | 129 (48.3) | 3.464 | 0.177 | | GA | 104 (46.2) | 105 (42.3) | | | 107 (48.6) | 108 (40.4) | | | | AA | 15 (6.7) | 26 (10.5) | | | 19 (8.6) | 30 (11.2) | | | | G | 316 (70.2) | 339 (68.3) | 0.390 | 0.532 | 295 (67.0) | 366 (68.5) | 0.247 | 0.619 | | A | 134 (29.8) | 157 (31.7) | | | 145 (33.0) | 168 (31.5) | | | | rs4648635 | | | | | | | | | | CC | 176 (78.2) | 198 (79.8) | — | 0.915 | 185 (84.1) | 216 (80.9) | — | 0.617 | | CT | 46 (20.4) | 47 (19.0) | | | 33 (15.0) | 49 (18.4) | | | | TT | 3 (1.3) | 3 (1.2) | | | 2 (0.9) | 2 (0.7) | | | | C | 398 (88.4) | 443 (89.3) | 0.181 | 0.671 | 403 (91.6) | 481 (90.1) | 0.661 | 0.416 | | T | 52 (11.6) | 53 (10.7) | | | 37 (8.4) | 53 (9.9) | | |
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SCZ: schizophrenic; HC: healthy control. Fisher’s exact test. |
