Research Article
AK4 Promotes the Progression of HER2-Positive Breast Cancer by Facilitating Cell Proliferation and Invasion
Table 1
Relationships of AK4 and clinicopathological characteristics in 98 patients with HER2 overexpression breast cancer.
| Features | All | AK4 expression | | | Low | High | () | () |
| Age (year) | | | | 0.331 | 0.565 | <50 | 50 | 18 | 32 | | | ≥50 | 48 | 20 | 28 | | | Tumor grade | | | | 0.653 | 0.419 | Low | 54 | 19 | 35 | | | High | 44 | 19 | 25 | | | Tumor size | | | | 0.917 | 0.338 | <2 | 56 | 24 | 32 | | | ≥2 | 42 | 14 | 28 | | | pTNM stage | | | | 5.674 | 0.017 | I-II | 62 | 30 | 32 | | | III-IV | 36 | 8 | 26 | | | Lymph node metastasis | | | | 3.967 | 0.046 | Yes | 46 | 12 | 34 | | | No | 52 | 22 | 26 | | | Vascular invasion | | | | 2.421 | 0.120 | Yes | 42 | 20 | 22 | | | No | 56 | 18 | 38 | | |
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