High SALM3 Expression in Tumor Cells and Fibroblasts Is Correlated with Poor Prognosis in Gastric Cancer Patients

Figure 1

High expression of SALM3 in gastric cancer cells and fibroblasts. (a) Representative images of SALM3 expression in benign and malignant gastric tissue samples: positive tumor cytoplasm (purple arrow), fibroblasts (yellow arrow), and negative staining (blue arrow) of immunohistochemical staining of SALM3. Rows 1 and 2 are SALM3 staining at a magnification of 400x (bar = 50 μm) and 40x (bar = 500 μm), respectively. (b) Box plots from gene expression data in Oncomine comparing the expression of SALM3 in normal and GC tissues. The value was set up at 0.01, and fold change was defined as 2. (c) A meta-analysis of SALM3 gene expression from 3 Oncomine databases, where colored squares indicate the median rank for SALM3 (vs. normal tissue) across 7 analyses: Cho’s gastric (1-3), DErrico’s gastric (4-6), and Wang’s gastric (7). The value is given for the median-rank analysis.

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