Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia

Figure 4

Western blot and immunohistochemical staining analyses of the NEMO protein in placentas from early, late preeclampsia, and noncomplicated pregnancies. Western blot analyses of the NEMO protein for total homogenates (a), cytoplasmic fraction (b), and nuclear fraction (c). The western blot analyses are presented as mean ± SEM ( for each subfraction). Asterisks indicate significant differences ( value < 0.05) between late preeclampsia and control. Immunostaining of NEMO in early preeclampsia (d), late preeclampsia (e), and control placentas (f). The histograms (g, h) represent the median value and interquartile range of the optical density (OD) of the NEMO protein between whole preeclamptic and control groups (g) and between the early preeclamptic group, late preeclamptic group, and control (h). The OD density is given on an arbitrary scale in arbitrary units (a.u.). Asterisks indicate significant differences ().

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