Review Article
A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
Table 3
Salivary biomarkers in periodontitis.
| Salivary biomarker | Function | References |
| IL-1 | Strong relation with periodontal disease; high inflammatory potential | [25, 28–33, 45] | IL-6 | Stimulates osteoclastic differentiation; increased levels in periodontal disease; regulated the immune responses | [34–38, 45] | Tumor necrosis factor | Influences the bone collagen synthesis | [28, 39, 45] | Matrix metalloproteinase-9 | Mediator of the immune response and tissue destruction in periodontal disease | [40–43] |
|
|