Research Article

The Diagnostic and Prognostic Value of miR-200c in Gastric Cancer: A Meta-Analysis

Table 1

Characteristics of the studies that related to the diagnosis of gastric cancer.

StudyCountry/yearDesignSample typeTumor/controlStageCut-offTest methodSensitivitySpecificityQUADAS

Tseng CWChina/2011RTissue22/22I-IV2670.5Microarray54.5%54.5%10
Valladares-AyerbesSpain/2012RBlood52/15I-IV62.4qRT-PCR65.4%100%13
Lin GYChina/2013RBlood50/50I-IV0.12qRT-PCR67.5%78.5%11
Tang JLChina/2015RBlood47/50I-IV1.285qRT-PCR97.0%54.0%12
Keller AGermany/2014RTissue11/93I-IV101.04Microarray72.7%55.9%12
Sierzega MPoland/2017RTissue20/20I-IV0.342Microarray60.0%45.0%13

R: retrospective; QUADAS: quality assessment of diagnostic accuracy studies.