The Diagnostic and Prognostic Value of miR-200c in Gastric Cancer: A Meta-Analysis

Table 2

Characteristics of the studies that related to the prognosis of gastric cancer.

Study	Country/year	Design	Sample	Number	Stage	Cut-off	Test method	Outcome	HR	95% CI	QUADAS
Valladares-Ayerbes	Spain/2012	R	Blood	52	I-IV	104.8	qRT-PCR	OS	2.24	1.091-4.614	13
								PFS	2.27	1.093-4.712
Tang HL	China/2013	R	Tissue	126	I-IV	2.00	qRT-PCR	OS	2.29	1.38-3.81	11
								DFS	1.83	1.15-2.92
Blanco-Calvo	Spain 2014	R	Blood	42	I-IV	Median	qRT-PCR	OS	2.24	1.091-4.614	12
								PFS	2.27	1.093-4.712
Song FJ	China/2014	R	Blood	385	I-IV	Median	qRT-PCR	OS	1.32	0.82-2.12	12
								PFS	1.06	0.70-1.60
Zhang HP	China/2015	R	Blood	98	I-IV	Median	qRT-PCR	OS	4.01	2.67-10.02	11
Zhou X	China/2015	R	Tissue	63	IIB-IV	Median	qRT-PCR	DFS	1.70	1.21-2.38	12
Zhang L	China/2017	R	Tissue	169	I-IV	Median	qRT-PCR	DFS	1.58	0.72–3.44	13

R: retrospective; QUADAS: quality assessment of diagnostic accuracy studies; OS: overall survival; PFS: progression-free survival; DFS: disease-free survival.