Research Article

Predicting Long-Term Mortality after Acute Coronary Syndrome Using Machine Learning Techniques and Hematological Markers

Table 2

Baseline characteristics according to the survival or death status–numerical variables. Data is presented as median and interquartile range (IQR). values refer to the results of the two-tailed Mann-Whitney test.

Survival ()Death () value

Age (years)65.5 (59.4-73.0)72.1 (64.4-79.8)<0.001
Troponin elevation (ratio)0.9 (0.4-3.9)3.1 (0.7-38.2)<0.001
Systolic blood pressure (mmHg)120.0 (110.0-130.0)117.0 (110.0-130.0)<0.001
Diastolic blood pressure (mmHg)80.0 (75.0-90.0)78.0 (70.0-85.0)<0.001
Heart rate at admission72.0 (64.0-83.0)76.0 (66.0-89.0)<0.001
C-reactive protein (mg/dl)0.4 (0.2-1.8)2.2 (0.6-6.4)<0.001
Fibrinogen (mg/dl)398.0 (344.0-467.0)430.0 (363.8-517.2)<0.001
Creatinine (mg/dl)1.0 (0.8-1.1)1.1 (0.9-1.4)<0.001
Neutrophil (103/mm3)5.1 (3.9-6.6)6.1 (4.5-8.6)<0.001
Lymphocyte (103/mm3)1.9 (1.5-2.4)1.6 (1.2-2.2)<0.001
Monocyte (103/mm3)0.6 (0.5-0.7)0.7 (0.5-0.9)<0.001
Eosinophil (103/mm3)0.1 (0.1-0.2)0.1 (0.0-0.2)<0.001
Hematocrit (%)42.7 (39.8-45.4)40.3 (35.9-43.9)<0.001
Hemoglobin (g/dl)14.5 (13.5-15.5)13.5 (11.9-14.8)<0.001
Red cell distribution width12.2 (11.6-12.9)12.8 (12.0-14.0)<0.001
Mean cell volume (fl)91.1 (88.2-94.4)91.6 (88.1-95.2)0.1
Platelets (103/mm3)221.0 (186.0-261.0)223.0 (174.2-269.0)0.72
Mean platelet volume (fl)8.6 (7.5-9.8)8.3 (7.3-9.6)0.001
Alanine aminotransferase (U/l)24.0 (17.0-34.0)23.0 (16.0-37.0)0.01
Aspartate aminotransferase (U/s)24.0 (19.0-32.0)28.0 (20.0-52.0)<0.001
Basophil count (103/mm3)0.1 (0.1-0.1)0.1 (0.0-0.1)0.02
Cholesterol level (mg/dl)175.0 (144.0-216.0)162.0 (135.0-198.0)<0.001
Low-density lipoprotein (mg/dl)106.0 (78.0-143.0)97.0 (73.0-127.0)<0.001
High-density lipoprotein (mg/dl)50.0 (41.0-60.0)46.0 (37.0-57.0)<0.001
Triglycerides (mg/dl)122.0 (88.0-172.0)105.0 (79.8-149.2)0.04
Sodium (mmol/l)141.0 (139.0-143.0)140.0 (138.0-142.0)<0.001
Potassium (mmol/l)4.4 (4.1-4.7)4.4 (4.1-4.8)0.01
Urea (mg/dl)36.0 (30.0-45.0)47.0 (36.0-65.2)0.4
Neutrophil to lymphocyte ratio2.6 (1.9-3.7)3.6 (2.4-5.9)<0.001
Platelet to lymphocyte ratio114.4 (87.8-149.6)131.6 (94.4-187.3)<0.001
Days of hospitalization4.0 (3.0-5.0)4.0 (3.0-7.0)<0.001