Research Article

A Low Ankle-Brachial Index and High Brachial-Ankle Pulse Wave Velocity Are Associated with Poor Cognitive Function in Patients Undergoing Hemodialysis

Table 2

The association between ABI and cognitive function test (MoCA and CASI) using univariate linear regression analysis and multivariate stepwise linear regression analysis.

Cognitive function testUnivariateMultivariate (stepwise)
β coefficient (95% CI) valueβ coefficient (95% CI) value

MoCA1.07 (0.55 to 1.59)<0.0010.62 (0.14 to 1.09)0.011
CASI2.87 (1.45 to 4.29)<0.0011.43 (0.17 to 2.70)0.026

Adjusting for stepwise procedure selected covariates (age, sex, smoking habit, a history of diabetes, hypertension, coronary artery disease, and cerebrovascular disease, systolic and diastolic blood pressures, body mass index, log-transformed hemodialysis duration, cause of end-stage renal disease, albumin, log-transformed triglyceride, total cholesterol, hemoglobin, creatinine and calcium-phosphorus product, Kt/V, and amount of ultrafiltration).