Research Article
High Lipoprotein(a) Level Is Independently Associated with Adverse Clinicopathological Features in Patients with Prostate Cancer
Table 1
Baseline characteristics of the study subjects according to the risk of PCa.
| | All subjects () | Low-intermediate risk () | High risk () | value |
| | Demographic characteristics | | | | | Age (years) | | | | 0.230 | | BMI (kg/m2) | | | | 0.639 | | Hypertension ( (%)) | 140 (37.2) | 19 (35.2) | 121 (37.6) | 0.764 | | Diabetes mellitus ( (%)) | 49 (13.0) | 10 (18.5) | 39 (12.1) | 0.273 | | Coronary artery disease ( (%)) | 56 (14.9) | 6 (11.1) | 50 (15.5) | 0.424 | | Lipid-lowering drugs ( (%)) | 9 (2.4) | 2 (3.7) | 7 (2.2) | 0.623 | | Lipid parameters | | | | | | TG (mmol/l) | 1.04 (0.76-1.39) | 1.07 (0.68-1.49) | 1.04 (0.77-1.38) | 0.520 | | TC (mmol/l) | | | | 0.634 | | LDL-C (mmol/l) | | | | 0.359 | | HDL-C (mmol/l) | | | | 0.714 | | TC/HDL-C | | | | 0.213 | | LDL-C/HDL-C | | | | 0.141 | | RC (mmol/l) | | | | 0.903 | | Lp(a) (mg/l) | 216 (104-382) | 165 (71-334) | 224 (110-401) | 0.022 | | Surgery ( (%)) | | | | | | Radical prostatectomy | 75 (19.9) | 26 (48.1) | 49 (15.2) | <0.001 | | Bilateral orchiectomy | 55 (14.4) | 0 | 54 (16.8) | 0.001 |
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Data are expressed as (%), , or median (25th-75th percentile). The bold value indicated statistical significance. PCa = prostate cancer; BMI = body mass index; PSA = prostate-specific antigen; RC = remnant cholesterol; TC = total cholesterol; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; TG = triglycerides; Lp(a) = lipoprotein(a). |
