High Lipoprotein(a) Level Is Independently Associated with Adverse Clinicopathological Features in Patients with Prostate Cancer
Table 3
Demographic and clinicopathological characteristics of study subjects according to the quartiles of Lp(a) plasma levels.
Quartiles of Lp(a)
<104 ()
104-216 ()
216-381 ()
>381 ()
value
Demographic characteristics
Age (years)
0.668
BMI (kg/m2)
0.001
Hypertension ( (%))
48 (50.5)
30 (32.3)
34 (36.2)
28 (29.8)
0.015
Diabetes mellitus ( (%))
11 (11.6)
11 (11.8)
9 (9.6)
18 (19.1)
0.222
Coronary artery disease ( (%))
14 (14.7)
13 (14.0)
15 (16.0)
14 (14.9)
0.989
Lipid-lowering drugs ( (%))
4 (4.2)
3 (3.2)
1 (1.1)
1 (1.1)
0.424
Clinicopathological characteristics
( (%))
29 (30.5)
39 (42.4)
44 (46.8)
44 (46.8)
0.075
ISUP grade ( (%))
0.837
1
14 (14.7)
7 (7.5)
11 (11.7)
9 (9.6)
2
7 (7.4)
7 (7.5)
6 (6.4)
10 (10.6)
3
13 (13.7)
11 (11.8)
12 (12.8)
12 (12.8)
4
25 (26.3)
24 (25.8)
27 (28.7)
18 (19.1)
5
36 (37.9)
44 (47.3)
38 (40.4)
45 (47.9)
Stage ( (%))
0.017
T1
7 (7.4)
3 (3.2)
3 (3.2)
2 (2.1)
T2
57 (60.0)
44 (47.3)
47 (50.0)
57 (60.6)
T3
24 (25.3)
35 (37.6)
22 (23.4)
22 (23.4)
T4
7 (7.4)
11 (11.8)
22 (23.4)
13 (13.8)
N1
23 (24.2)
28 (30.1)
37 (39.4)
33 (35.1)
0.137
M1
27 (28.4)
41 (44.1)
45 (47.9)
45 (47.9)
0.018
Data are expressed as (%), , or median (25th-75th percentile). The bold value indicated statistical significance. PCa = prostate cancer; BMI = body mass index; PSA = prostate-specific antigen; ISUP = International Society of Urological Pathology.