Research Article

High Lipoprotein(a) Level Is Independently Associated with Adverse Clinicopathological Features in Patients with Prostate Cancer

Table 3

Demographic and clinicopathological characteristics of study subjects according to the quartiles of Lp(a) plasma levels.

Quartiles of Lp(a)
<104 ()104-216 ()216-381 ()>381 () value

Demographic characteristics
 Age (years)0.668
 BMI (kg/m2)0.001
 Hypertension ( (%))48 (50.5)30 (32.3)34 (36.2)28 (29.8)0.015
 Diabetes mellitus ( (%))11 (11.6)11 (11.8)9 (9.6)18 (19.1)0.222
 Coronary artery disease ( (%))14 (14.7)13 (14.0)15 (16.0)14 (14.9)0.989
 Lipid-lowering drugs ( (%))4 (4.2)3 (3.2)1 (1.1)1 (1.1)0.424
Clinicopathological characteristics
( (%))29 (30.5)39 (42.4)44 (46.8)44 (46.8)0.075
 ISUP grade ( (%))0.837
  114 (14.7)7 (7.5)11 (11.7)9 (9.6)
  27 (7.4)7 (7.5)6 (6.4)10 (10.6)
  313 (13.7)11 (11.8)12 (12.8)12 (12.8)
  425 (26.3)24 (25.8)27 (28.7)18 (19.1)
  536 (37.9)44 (47.3)38 (40.4)45 (47.9)
 Stage ( (%))0.017
  T17 (7.4)3 (3.2)3 (3.2)2 (2.1)
  T257 (60.0)44 (47.3)47 (50.0)57 (60.6)
  T324 (25.3)35 (37.6)22 (23.4)22 (23.4)
  T47 (7.4)11 (11.8)22 (23.4)13 (13.8)
  N123 (24.2)28 (30.1)37 (39.4)33 (35.1)0.137
  M127 (28.4)41 (44.1)45 (47.9)45 (47.9)0.018

Data are expressed as (%), , or median (25th-75th percentile). The bold value indicated statistical significance. PCa = prostate cancer; BMI = body mass index; PSA = prostate-specific antigen; ISUP = International Society of Urological Pathology.