Replication of GWAS Loci Revealed an Increased Risk of BET1L and H19 Polymorphisms with Intracranial Aneurysm

Table 1

Demographics of controls and patients with IA.

	Controls	Patients with IA	value
Age (year, )			0.26
Gender
Male	217 (36.9)	213 (39.3)	0.41
Female	371 (63.1)	329 (60.7)
Systolic pressure (mmHg, )			0.25
Diastolic pressure (mmHg, )			0.90
TC (mmol/L, )			<0.001
TG (mmol/L, )			0.07
HDL-C (mmol/L, )			<0.001
LDL-C (mmol/L, )			<0.001
Multiple aneurysm
Yes		74 (13.7)
No		468 (86.3)
Rupture of aneurysm
Yes		477 (88.0)
No		65 (12.0)
Familial aneurysm
Yes		54 (10.0)
No		488 (90.0)

IA: intracranial aneurysm; SD: standard deviation; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.