Haplotypes of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 Gene Polymorphisms in Age-Related Macular Degeneration

Table 6

Haplotypes associated with AMD.

Single-nucleotide polymorphisms	Haplotype	Frequency (cases)	Frequency (controls)	Chi square	Degree of freedom	value
Early AMD
rs3793784-rs11200638	C-A	0.1343	0.1014	9.554	1	0.051
	G-A	0.2196	0.1771	3.485	1	0.054
	C-G	0.2569	0.2586	0.004	1	0.943
	G-G	0.3892	0.4629	6.840	1	0.007
Exudative AMD
rs3793784-rs11200638	C-A	0.2371	0.1069	36.30	1	<0.001
	G-A	0.3077	0.1716	30.97	1	<0.001
	C-G	0.1765	0.2530	10.55	1	<0.001
	G-G	0.2787	0.4685	46.75	1	<0.001

value adjusted for age in exudative AMD analysis; values < 0.008 indicated in bold are statistically significant.