Research Article
Association between the -844 G>A, HindIII C>G, and 4G/5G PAI-1 Polymorphisms and Susceptibility to Multiple Sclerosis in Western Mexican Population
Table 2
Allele and genotype distributions of -844 G>A, HindIII C>G, and 4G/5G PAI-1 polymorphisms in MS and CS.
| | Polymorphism | MS % () | CS % () | OR (CI 95%); |
| | -844 G>A | | | | | Genotype | | | | | GG | 40 (80) | 45.5 (91) | 1 | | GA | 52.5 (105) | 44.5 (89) | 1.3 (0.88-2.02); 0.16 | | AA | 7.5 (15) | 10 (20) | 0.8 (0.41-1.77); 0.67 | | Allele | | | | | G | 33.8 (135) | 67.8 (271) | 1 | | A | 66.2 (265) | 32.2 (129) | 1.1 (0.79-1.43); 0.65 | | HindIII C>G | | | | | Genotype | | | | | CC | 44 (88) | 50.5 (101) | 1 | | CG | 47 (94) | 34 (68) | 1.58 (1.04-2.42); 0.03 | | GG | 9 (18) | 10.5 (21) | 0.98 (0.49-1.964); 0.96 | | Allele | | | | | G | 32.5 (130) | 30 (120) | 1.12 (0.833-1.515); 0.44 | | C | 67.5 (270) | 70 (280) | 1 | | 4G/5G | | | | | Genotype | | | | | 4G/4G | 45.5 (91) | 44.5 (89) | 1.18 (0.79-1.79); 0.40 | | 4G/5G | 43 (86) | 50 (100) | 1 | | 5G/5G | 11.5 (23) | 5.5 (11) | 2.43 (1.12-5.27); 0.02 | | Allele | | | | | 4G | 67 (268) | 69.5 (278) | 1 | | 5G | 33 (132) | 30.5 (122) | 1.36 (1.01-1.83); 0.04 |
|
|
MS: multiple sclerosis; CS: control subjects; OR: odds ratio; CI: confidence interval. . |
