Diagnostic Accuracy of circRNAs in Esophageal Cancer: A Meta-Analysis

Table 1

Main characteristics of the included studies in this meta-analysis.

References	Year	Country	Case/control	circRNAs	Regulation	Cancer type	Specimen	Sensitivity (%)	Specificity (%)	AUC	TP	FP	FN	TN	QUADAS-2
Rong et al.	2018	China	35/28	circ-DLG1	Upregulated	ESCC	Plasma	83.0	50.0	0.648	29	14	6	14	7
Fan et al.	2019	China	50/50	hsa_circ_0001946	Downregulated	ESCC	Plasma	92.0	80.0	0.894	46	10	4	40	8
				hsa_circ_0062459	Downregulated	ESCC	Plasma	64.0	92.0	0.836	32	4	18	46
Wang et al.	2019	China	30/25	circ-TTC17	Upregulated	ESCC	Plasma	73.3	88.0	0.820	22	3	8	22	7
Zhang et al.	2019	China	32/25	circ-SMAD7	Downregulated	ESCC	Plasma	78.0	96.0	0.859	25	1	7	24	6

ESCC: esophageal squamous cell carcinoma; AUC: area under the receiver operating characteristic curve; TP: true positive; FP: false positive; FN: false negative; TN: true negative.