|
| Author (year) | Study groups | | Sex | Age | Subgroup analysis within SLE | MMP-3 in SLE | MMP-3 in HC | ELISA kit used |
| M/F | Mean (SD or range) | Mean (SD or range) | Mean (SD or range) |
|
| Jin et al. (2013) [15] | SLE | 31 | 0/31 | 48.7 (12.7) | — | 25.2 (23.4) | 10.2 (4.4) | Quantikine; R&D Systems Inc., UK |
| HC | 150 | 0/150 | 45.8 (11.3) |
|
| Zhu et al. (2015) | SLE | 60 | 3/57 | 33.3 (10.8) | — | 21.4 (7.3) | 14.4 (8.4) | Quantikine; R&D Systems Inc., UK |
| HC | 60 | 3/57 | 33.4 (10.9) |
|
| De Leeuw et al. (2006) [16] | SLE | 72 | 9/63 | 41.0 (12.0) | — | 19 (14.1) | 8.0 (4.4) | BioSource, Europe S.A., Belgium |
| HC | 36 | 3/33 | 41.0 (12.0) |
|
| Ribbens et al. (2002) [17] | Cutaneous lupus | 7 | 0/7 | 34 (15-57) | Cutaneous lupus | 11.5 (4.4) (female data) | 9.2 (2.8) | BioSource, Europe S.A., Belgium |
| Renal lupus | 7 | 2/5 | 30 (15-54) | Renal lupus |
| HC | 96 | 50/46 | 44 (25-64) | |
|
| Zucker et al. (1999) [12] | SLE | 73 | N/A | N/A | — | 416.0 (252.0) | 125.0 (93.0) | In-house method using human Ab (Mac078, Celltech) |
| HC | 39 | N/A | N/A |
|
| Ichikawa et al. (1998) [18] | SLE | 21 | 3/18 | 38.2 (13.5) | — | 239.1 (199.6) | 63 (64.1) | Fuji Chemical Industries Ltd., Toyama, Japan |
| HC | 20 | 0/20 | 56.8 (4.6) |
|
| Kotajima et al. (1998) | SLE | 124 | 8/116 | N/A | With or without dsDNA | 193.0 (171.5) | 61.8 (33.9) | In-house method using human Ab (NB1RGB) |
| HC | 117 | 67/50 | N/A |
|
| Akiyama et al. (1997) [19] | SLE | 13 | 5/7 | 35.6 (3.5) | — | 155.7 (23.4) | 61.7 (3.15) | Fuji Chemical Industries Ltd., Toyama, Japan |
| HC | 154 | N/A | N/A |
|
| Shingu et al. (1995) [20] | SLE | 67 | 6/61 | 46.5 (15.6) | — | 117.3 (107.4) | 42.1 (29.2) | Fuji Chemical Industries Ltd., Toyama, Japan |
| HC | 170 | 50/120 | N/A |
|
| Zucker et al. (1994) [21] | SLE | 17 | 3/14 | 36.2 (N/A) | — | 258.4 (124.3) | 50.0 (124.3) | In-house method using human Ab (Mac078, Celltech) |
| HC | 53 | 30/23 | 42.0 (N/A) |
|
| Gheita et al. (2015) [22] | SLE | 42 | 0/42 | 33.2 (11.6) | With or without nephritis | 80.9 (45.8) | 10.01 (2.6) | N/A |
| HC | 30 | 0/30 | N/A |
|
| KPS study (unpublished) | SLE | 11 | 3/8 | 14.5 (11.8-18) | With vs. without nephritis | 195.3 (50.3) | 26.4 (19.3) | Ab Frontier, Seoul, Korea |
| HC | 9 | 2/7 | 12.2 (10.0-15.0) | With vs. without dsDNA |
|
