Plasma miR-208b and miR-499: Potential Biomarkers for Severity of Coronary Artery Disease

Table 3

Logistic regression analysis for determining the independent predictors of high SS.

Variables	OR	95% CI	value	Adjusted OR	95% CI	value
Male gender	0.949	0.529-1.702	0.861
Age	1.023	0.995-1.052	0.109
Hypertension	1.113	0.627-2.039	0.684
Diabetes mellitus	1.917	0.968-3.796	0.062
Current smoking	1.967	1.088-3.557	0.025	2.019	0.805-5.064	0.134
Heart rate	1.036	1.013-1.060	0.002	1.031	0.994-1.069	0.099
Hemoglobin	0.985	0.968-1.004	0.126
Leukocyte	1.472	1.230-1.761	<0.001	1.355	1.051-1.747	0.019
Hs-CRP	1.045	1.017-1.074	0.001	1.043	1.003-1.085	0.035
Creatinine	0.997	0.978-1.016	0.743
CK-MB	1.125	1.067-1.185	<0.001	1.129	1.054-1.209	0.001
LDL-cholesterol	0.814	0.530-1.251	0.349
HDL-cholesterol	0.215	0.069-0.664	0.008	0.336	0.060-1.884	0.215
Total cholesterol	0.987	0.774-1.259	0.919
miRNA-208b	2.553	1.863-3.499	<0.001	2.069	1.351-3.167	0.001
miRNA-499	1.644	1.347-2.008	<0.001	1.652	1.222-2.233	0.001

Abbreviation: SS: synergy between percutaneous coronary intervention with taxus and cardiac surgery score; OR: odds ratio; CI: confidence interval; Hs-CRP: high-sensitivity C-reactive protein; CK-MB: creatine kinase isoenzyme; LDL: low-density lipoprotein; HDL: high-density lipoprotein.