Research Article

Serum Irisin Predicts Posthepatectomy Complications in Patients with Hepatocellular Carcinoma

Table 1

Demographic data, coexistences, laboratory results, and imaging findings in HCC patients.

VariableTotal (N = 117) μg/ml (N = 27) μg/ml (N = 90) value

Age (years, )0.905
Gender (male/female)94/2318/976/140.041
BMI (kg/m2, )0.468
Coexistences (, %)
 Smoking59 (50.4)13 (48.1)46 (51.1)0.787
 Drinking40 (34.2)9 (33.3)31 (34.4)0.915
 Hypertension24 (20.5)8 (29.6)16 (17.8)0.181
 Diabetes mellitus10 (8.5)2 (7.4)8 (8.9)0.809
 Virus hepatitis86 (73.5)13 (48.1)73 (81.1)0.001
 Cirrhosis62 (53.0)12 (44.4)50 (55.6)0.310
Laboratory results ( or median, interquartile range)
 AFP (ng/ml)111.2 (4.7-106.8)11.2 (3.0-295.5)166.3 (5.3-2616.8)0.030
 Leucocytes (×109/l)0.477
 Hemoglobin (g/l)0.580
 Platelet count (×109/l)0.263
 ALT (U/l)39.3 (22.5-62.9)38.0 (22.8-71.1)40.0 (22.1-60.1)0.313
 AST (U/l)38.0 (25.3-58.3)37.9 (25.0-60.2)38.3 (25.8-58.4)0.779
 ALP (U/l)101.8 (73.8-132.8)102.9 (71.0-124.0)102.0 (74.6-136.0)0.876
 GGT (U/l)73.5 (41.6-136.8)66.0 (45.6-135.32)79.4 (39.2-140.5)0.954
 TBIL (μmol/l)0.932
 DBIL (μmol/l)0.422
 ALB (g/l)0.916
 Cr (μmol/l)0.093
 BUN (mmol/l)0.804
 PT (s)0.112
 INR0.063
Imaging findings ( or )
 Tumor size (cm)0.137
 Single/multiple tumor94/2321/673/170.702
 TNM stage (I, II/III, IV)48/6912/1535/550.606

BMI: body mass index; AFP: alpha-fetoprotein; ALT: alanine transaminase; AST: aspartate transaminase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; TBIL: total bilirubin; DBIL: direct bilirubin; ALB: albumin; Cr: creatinine; BUN: blood urea nitrogen; PT: prothrombin time; INR: international normalized ratio.