Association of Polymorphisms in RANK and RANKL Genes with Osteopenia in Arab Postmenopausal Women

Table 3

Association between osteopenia and RANKL SNP.

SNP	Control (%)	Osteopenia (%)	Osteopenia
			OR (95% confidence interval)	value
rs2277438
GG	10 (5.0)	70 (48.3)	20.56 (9.82–43.06)	<0.001
AG	49 (24.5)	27 (18.6)	1.62 (0.91–2.87)	0.09
AA	141 (70.2)	48 (33.1)	1
G	69 (17.3)	167 (57.5)	4.54 (3.18–6.49)	<0.001
A	231 (82.7)	123 (42.4)	1
rs9533156
TT	92 (36.9)	79 (31.7)	1
TC	82 (31.3)	97 (37.0)	1.38 (0.91–2.10)	0.14
CC	42 (38.5)	39 (35.8)	1.08 (0.64–1.84)	0.77
T	266 (61.6)	255 (59.3)	1
C	166 (38.4)	175 (40.7)	1.10 (0.84–1.44)	0.50

Note: data are presented as frequencies (%) and OR (95% CI). value <0.05 is considered significant.