Research Article

The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection

Table 1

Demographic and clinical data of 674 ESCC patients according to LMR change.

Characteristics (%)LMRc value
≤1.59 (%)>1.59 () (%)

Sex
 Male576 (85.5)307 (91.1)269 (79.8)<0.001
 Female98 (14.5)30 (8.9)68 (20.2)
Age
 ≤60 years310 (46.0)146 (43.3)164 (48.7)0.164
 >60 years364 (54.0)191 (56.7)173 (51.3)
Pathology grade
 Well49 (7.4)23 (7.0)26 (7.8)0.304
 Middle446 (67.5)231 (70.0)215 (65.0)
 Poorly164 (24.8)76 (23.0)88 (26.6)
 Undifferentiated2 (0.3)0 (0)2 (0.6)
Depth of tumor
 T1a–1b64 (9.5)29 (8.6)35 (10.4)0.670
 T2129 (19.1)63 (18.7)66 (19.6)
 T3481 (71.4)245 (72.7)236 (70.0)
Lymph node metastasis
 N0293 (43.5)150 (44.5)143 (42.4)0.142
 N1212 (31.5)101 (30.0)111 (32.9)
 N2117 (17.4)53 (15.7)64 (19.0)
 N352 (7.7)33 (9.8)19 (5.6)
Pathological stage
 1a–1b115 (17.1)56 (16.6)59 (17.5)0.949
 2a–2b226 (33.5)113 (33.5)113 (33.5)
 3a–3c333 (49.4)168 (49.9)165 (49.0)
Vessel invasive
 Yes206 (30.6)101 (30.0)105 (31.2)0.738
 No468 (69.4)236 (70.0)232 (68.8)
Nerve infiltration
 Yes251 (37.2)125 (37.1)126 (37.4)0.936
 No423 (62.8)212 (62.9)211 (62.6)
Treatment regimen
 S457 (67.8)224 (66.5)233 (69.1)0.757
 S+postoperative C155 (23.0)81 (24.0)74 (22.0)
 S+postoperative CRT62 (9.2)32 (9.5)30 (8.9)
Hospital time
 ≤14 days560 (83.1)265 (78.6)295 (87.5)0.002
 >14 days114 (16.9)72 (21.4)42 (12.5)
NLRc
 Median-3.02 (-4.64–-1.69)-2.26 (-3.93–-0.95)-3.78 (-5.39–-2.49)<0.001
LMRc
 Median1.59 (0.71-2.69)0.71 (0.05-1.19)2.68 (2.02-3.54)<0.001
PLRc
 Median-104.89 (-162.16–-54.85)-100.65 (-159.19–-38.38)-108.64 (-163.21–-72.47)0.003