Tissue Infiltrating Immune Cells as Prognostic Biomarkers in Endometrial Cancer: A Meta-Analysis

Table 2

Meta-analysis of immune cells and prognostic indices in EC patients.

Group	Study number	Number of case	Pooled result, HR (95% CI)	PZ value	PH value
CD8-OS	5	740	0.201 (0.076-0.533)	0.001	0.104	45.2%
CD8-PFS-a/b	3	397	0.308 (0.139-0.683)/0.306 (0.137-0.687)	0.004	0.555/0.554	0.0%
CD8-DSS	2	673	0.366 (0.222-0.604)	0.000	0.353	0.0%
CD8-DFS	2	673	0.466 (0.329-0.660)	0.000	0.396	0.0%
FoxP3^+ T cell-OS	3	352	1.264 (0.419-3.812)	0.678	0.212	35.6%
FoxP3^+ T cell-RFS	2	273	1.000 (0.995-1.005)	0.999	0.655	0.0%
CD45RO^+ T cell-OS	2	478	0.415 (0.241-0.714)	0.001	0.638	0.0%
TAM-OS	3	425	1.985 (0.771-5.113)	0.156	0.628	0.0%
TAM-RFS-c/d	4	479	3.423 (1.289-9.094)/1.770 (0.458-6.843)	0.014/0.408	0.364/0.068	5.9%/57.8%
TAM-RFS-e/f	4	479	2.369 (1.003-5.598)/2.258 (0.966-5.282)	0.049/0.06	0.403/0.373	0.0%/3.9%

PZ: value of the -test; PH: value of the heterogeneity test.