Prognostic Role of Serum Amino Acids in Head and Neck Cancer

Table 2

Odds ratios (ORs) and 95% confidence interval (95% CI) for advanced vs. early stage of HNC.

Amino acid	ORs (95% CI)	value
Alanine	0.47 (0.19-1.12)	0.089
Alpha-aminobutyric acid	0.40 (0.16-0.98)	0.045
Aminoadipic acid	0.36 (0.17-0.78)	0.010
Arginine	0.59 (0.32-1.11)	0.101
Asparagine	0.67 (0.37-1.23)	0.195
Beta-alanine	2.55 (1.17-5.60)	0.019
Beta-aminobutyric acid	1.91 (1.00-3.65)	0.048
Citrulline	0.68 (0.36-1.27)	0.228
Ethanolamine	2.25 (1.20-4.24)	0.012
Gamma-aminobutyric acid	nc	nc
Glycine	2.35 (1.17-4.73)	0.016
Histidine	0.40 (0.19-0.85)	0.018
Isoleucine	2.39 (1.20-4.76)	0.014
4-Hydroxyproline	3.16 (1.02-9.78)	0.047
Leucine	1.65 (0.85-3.19)	0.141
Lysine	2.13 (0.95-4.77)	0.066
Methionine	2.15 (0.73-6.26)	0.163
1-Methylhistidine	0.59 (0.32-1.11)	0.102
3-Methylhistidine	0.77 (0.38-1.58)	0.473
Phenylalanine	2.72 (1.42-5.21)	0.003
Phosphoethanolamine	nc	nc
Proline	0.24 (0.09-0.62)	0.003
Sarcosine	0.43 (0.15-1.21)	0.109
Serine	1.76 (0.95-3.26)	0.075
Threonine	0.42 (0.17-1.05)	0.064
Tryptophan	0.41 (0.22-0.76)	0.005
Tyrosine	0.44 (0.13-1.46)	0.181
Valine	1.30 (0.71-2.39)	0.399

^aOdds ratio adjusted for age, sex, smoking status, and alcohol drinking status. nc: not computable.