Low UGP2 Expression Is Associated with Tumour Progression and Predicts Poor Prognosis in Hepatocellular Carcinoma

Figure 2

UGP2 mRNA levels and protein expression are significantly downregulated in HCC. (a) The UGP2 expression level was significantly lower in HCC tissues than in adjacent nontumour tissues in the TCGA cohort and GEO datasets. (b) A representative IHC image of UGP2 expression in HCC and normal tissues. (c) Representative images of UGP2 staining in HCC tissues. (d) The UGP2 expression level in HCC tissues was lower than that in paired nontumour tissues in the ZZU HCC cohort. UGP2: uridine diphosphate-glucose pyrophosphorylase 2; TCGA: The Cancer Genome Atlas; HCC: hepatocellular carcinoma; GEO: Gene Expression Omnibus; IHC: immunohistochemistry.

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