Digital PCR for the Analysis of MYC Copy Number Variation in Lung Cancer
Table 3
MYC copy numbers regarding the analyzed clinicopathological parameters ().
Tumor
Characteristic
Group
(, 42.6%)
(, 57.4%)
value (chi2 test)
Age, (%)
≤67 years
31 (56.4)
34 (45.9)
0.242
>67 years
24 (43.6)
40 (54.1)
Sex, (%)
Male
34 (61.8)
46 (62.2)
0.968
Female
21 (38.2)
28 (37.8)
Smoking status, (%)
Never
7 (12.7)
8 (10.8)
0.929
Former
29 (52.7)
41 (55.4)
Current
19 (34.6)
25 (33.8)
Histological subtypes, (%)
Adenocarcinoma
29 (52.7)
38 (51.4)
0.338
Squamous cell carcinoma
12 (21.8)
18 (24.3)
Carcinoid
4 (7.3)
10 (13.5)
LCNEC#
6 (10.9)
2 (2.7)
Other§
4 (7.3)
6 (8.1)
Grade, (%)
Missing
5 (9.1)
8 (10.8)
0.441
23 (41.8)
38 (51.4)
27 (49.1)
28 (37.8)
T stage, (%)
Missing
2 (3.6)
1 (1.4)
0.092
T1
22 (40.0)
40 (54.0)
T2
25 (45.5)
20 (27.0)
6 (10.9)
13 (17.6)
Fisher’s exact test. #LCNEC: large-cell neuroendocrine carcinoma. §Four adenosquamous carcinomas, two non-small-cell lung cancers, one non-small-cell lung cancer (not otherwise specified), two small-cell carcinomas, and one synovial sarcoma.
