Lack of Efficacy of Combined Carbohydrate Antigen Markers for Lung Cancer Diagnosis

Table 6

Diagnostic efficacy of biomarkers with SCLC.

Biomarkers	Sensitivity	Specificity	PPV	NPV	AUC (95% CI)
CYFR21	0.586	0.732	0.472	0.813	0.783 (0.672-0.894)
CEA	0.607	0.827	0.459	0.897	0.808 (0.711-0.905)
NSE	0.690	0.757	0.526	0.862	0.819 (0.696-0.943)
SCC	0.074	0.848	0.125	0.757	0.557 (0.425-0.690)
CA125	0.269	0.879	0.412	0.793	0.633 (0.498-0.768)
CA15-3	0.160	0.951	0.500	0.788	0.607 (0.466-0.748)
CA199	0.214	0.915	0.667	0.593	0.367 (0.238-0.497)
CA50	0.071	0.988	0.667	0.759	0.531 (0.387-0.674)
CA242	0.077	0.871	0.154	0.755	0.340 (0.213-0.467)
CA724	0.038	0.941	0.143	0.793	0.529 (0.385-0.673)
The panel 1	0.931	0.619	0.355	0.972	0.884 (0.794-0.945)
The panel 2	0.931	0.576	0.659	0.882	0.908 (0.822-0.961)
The panel 3	0.483	0.730	0.304	0.851	0.720 (0.609-0.814)
The panel 4	0.931	0.525	0.325	0.969	0.928 (0.848-0.973)