Disease Markers / 2020 / Article / Fig 3

Research Article

6,12-Diphenyl-3, 9-diazatetraasterane-1, 5, 7, 11-tetracarboxylate Inhibits Proliferation, Migration and Promotes Apoptosis in Ovarian Cancer Cells

Figure 3

The effect of DDTC on the EMT in ovarian cancer cells. The dosage of DDTC at 0.1 μM, 1 μM, and 10 μM in SKOV3 and A2780 cells. (a, b) DDTC increased the protein expression level of E-cadherin and decreased the protein expression level of N-cadherin and Vimentin in SKOV3 cells. (c, d) DDTC increased the protein expression level of E-cadherin and decreased the protein expression level of N-cadherin and Vimentin in A2780 cells. (e) DDTC decreased the mRNA expression level of N-cadherin and Vimentin in SKOV3 cells. (f) DDTC increased the mRNA expression level of E-cadherin and decreased the mRNA expression level of N-cadherin and Vimentin in A2780 cells.
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